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Artemisinin

Name: Artemisinin
SKU: 0

CAS No.: 63968-64-9
Molecular Formula: C15H22O5
Molecular Weight: 282.33

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product description

Artemisinin is an antimalarial agent with anticancer activity. It is an iron(II) oxide-reactive endoperoxide that generates reactive oxygen species (ROS) upon cleavage of its endoperoxide bridge. It reduces the growth of various P. falciparum strains in vitro (IC50s = 3.98-20.36 nM) and reduces parasitemia in mice infected with P. falciparum with a curative dose (CD50) value of 140 mg/kg. It also reduces P. berghei infection in mice (ED50 = 5.6 mg/kg per day).

Chemical Properties

Property	Value
Melting point	156-157 °C (lit.)
Alpha	76 º (c=0.5,MeOH)
Boiling point	344.94°C (rough estimate)
Density	1.0984 (rough estimate)
Refractive index	75 ° (C=0.5, MeOH)
Storage temp.	-20°C
Solubility	Soluble to 100mM in DMSO and to 75mM in ethanol
Form	White to off-white crystalline solid.
Color	Needles
Optical Rotation	[α]20/D +76°, c = 0.5 in methanol
Merck	14,817
Stability	Stable. Combustible. Incompatible with strong oxidizing agents, acids, acid chlorides, acid anhydrides. May absorb, and react with, carbon dioxide from the air.
InChI	InChI=1S/C15H22O5/c1-8-4-5-11-9(2)12(16)17-13-15(11)10(8)6-7-14(3,18-13)19-20-15/h8-11,13H,4-7H2,1-3H3/t8-,9-,10+,11+,13-,14-,15-/m1/s1
InChIKey	BLUAFEHZUWYNDE-NNWCWBAJSA-N
SMILES	O1[C@]23[C@@]4([H])O[C@@](C)(CC[C@@]2([H])[C@H](C)CC[C@@]3([H])[C@@H](C)C(=O)O4)O1
LogP	2.900

Safety Information

Property	Property
Safety Statements	22-24/25
WGK Germany	2
RTECS	KD4170000
HS Code	29322985
Toxicity	LD50 in mice (mg/kg): 5105 orally; 2800 i.m.; 1558 i.p. (Koch); LD50 in mice, rats (mg/kg): 4228, 5576 orally; 3840, 2571 i.m. (China Cooperative Research Group on Qinghaosu)

Product Usage

Artemisinin, a sesquiterpene lactone extracted from the sweet wormwood plant (Artemisia annua), is globally recognized as the most effective treatment for malaria. Its primary application is in the pharmaceutical industry, where it serves as the core active ingredient in Artemisinin-based Combination Therapies (ACTs), the World Health Organization's gold standard for treating multi-drug resistant malaria. Beyond its antimalarial role, it is increasingly utilized in biomedical research for its promising anti-tumor activities, specifically its ability to induce apoptosis in various cancer cell lines. In the nutraceutical sector, artemisinin is featured in specialized dietary supplements aimed at supporting immune function and addressing parasitic imbalances. Furthermore, it acts as a critical chemical precursor for the semi-synthesis of potent derivatives like artemether and artesunate, which offer improved solubility and bioavailability for clinical use.

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Shipping And Transportation

Delivery Time

Inventory 2-3 working days New manufacturing 7-10 working days

Mode of Transportation
1. By Air, fast but expensive.
2. By Sea, usual and economy.
3. By Train, suit for middle Asia countries.
4. By Express, suit for small package.
We only provide highest quality goods available, accompanied by after support!

Qualification Certificate

FAQ

Q1: What international standards do your products and services comply with?

A1: Our products fully comply with international standards such as REACH, MSDS, and COA, and we strictly implement the ISO9001 quality management system. We can also provide third-party testing reports (SGS, BV, etc.) according to customer needs.

Q2: How long does it take for goods to be delivered to my country?
A2: The delivery time depends on the transport mode and destination country. Generally, sea transport takes 15-30 days, air transport takes 3-7 days, and we will optimize the transport route to shorten the delivery time as much as possible.

Can you provide customs clearance services for dangerous chemicals?
A3: Yes. Our team is proficient in the customs clearance procedures for dangerous chemicals in various countries, and can provide professional compliant declaration and customs clearance services to ensure smooth customs clearance.

Q4: Do you provide customized product and service solutions?
A4: Yes. We can provide personalized product customization and export service solutions according to your specific needs (product specifications, application scenarios, procurement volume, etc.).

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