Quinine

Quinine

CAS No.:130-95-0
Molecular Formula:C20H24N2O2
Molecular Weight: 324.42
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product description
Quinine(130-95-0), an alkaloid derived from the bark of the cinchona tree, is a blood schizontocidal agent that is more toxic than chloroquine. Quinine is used to treat malaria caused by Plasmodium falciparum.  Plasmodium falciparum is a parasite that gets into the red blood cells in the body and causes malaria.  Quinine works by killing the parasite or preventing it from growing.  This medicine may be used alone or given together with one or more medicines for malaria.


Chemical Properties

PropertyValue

Melting point

173-175 °C(lit.)

Alpha

-172 º (c=1, EtOH)

Boiling point

462.75°C (rough estimate)

Density

1.1294 (rough estimate)

Bulk density

110-140kg/m3

Vapor pressure

0Pa at 25℃

Refractive index

1.6250 (estimate)

Fp

>110°C (>230°F)

Storage temp.

Keep in dark place,Inert atmosphere,Room temperature

Solubility

H2O: soluble

Form

Crystalline Powder

Pka

8.52(at 25℃)

Color

White

PH Range

Blue I uorescence (3.0) to weak violet I uorescence (5.0);Weak violet I uorescence (9.5) to nonI uorescence (10.0)

PH

9.0 (0.5g/l, H2O, 20℃)

Odor Type

Odorless

Optical Rotation

[α]25/D 165°, c = 2 in ethanol

Water Solubility

slightly soluble

Sensitive

Light Sensitive

Hydrolytic Sensitivity

2: reacts with aqueous acid

Merck

14,8061

BRN

91867

Major Application

Bird repellents, sunscreen, antimalarial agent, antiviral agent, antitumor agent, drug-coated coronaryagent, antiparasitic agent, treatment of epilepsy, skeletal muscle spasm, drug-coated coronary stent system

LogP

3.17 at 25℃

CAS DataBase Reference

130-95-0(CAS DataBase Reference)

NIST Chemistry Reference

Quinine(130-95-0)

EPA Substance Registry System

Quinine (130-95-0)


Safety Information

PropertyValue
Hazard symbolsXn, Xi
Hazard class codes36/37/38-42/43-22-20/22-20/21/22-36/38
Safety descriptions22-26-36/37-45-37/39-36-7
UN dangerous goods number1544
WGK Germany3
RTECS numberVA6020000
F8
TSCATSCA listed
Hazard class6.1(b)
Packing group(not specified)
HS code29392110
Storage class11 - Combustible solids
Hazard class (category)Acute toxicity, Category 4, Oral
Skin sensitization, Category 1
Hazardous substances data130-95-0 (Hazardous Substances Data)
Antimalarial useStill used primarily for treatment of plasmodium resistant to synthetic antimalarials. Also used as antipyretic for colds, influenza, and cramp; quinine may have toxic effects on the eye, apparently due to an immune reaction, and may also affect male reproductive capacity.
Toxicity(See antimalarial use description above)


Product Usage

Quinine, a natural alkaloid historically derived from cinchona bark, is a multifunctional compound with significant applications in medicine and the food industry. Its most critical role remains in the pharmaceutical sector, where it is a vital anti-malarial medication used to treat severe Plasmodium falciparum infections and as an ingredient in treatments for nocturnal leg cramps. In the food and beverage industry, Quinine is the signature bittering agent in tonic water and various bitter lemons, providing the quintessential flavor profile for classic cocktails. Beyond consumption, it is utilized in analytical chemistry as a standard fluorescence reference due to its highly predictable quantum yield under UV light. Additionally, its unique chemical properties allow it to serve as a chiral resolving agent in asymmetric organic synthesis, assisting in the production of pure enantiomers for advanced drug manufacturing.

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Delivery Time

Inventory 2-3 working days New manufacturing 7-10 working days

Mode of Transportation
1. By Air, fast but expensive.
2. By Sea, usual and economy.
3. By Train, suit for middle Asia countries.
4. By Express, suit for small package.
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FAQ

Q1: What international standards do your products and services comply with?

A1: Our products fully comply with international standards such as REACH, MSDS, and COA, and we strictly implement the ISO9001 quality management system. We can also provide third-party testing reports (SGS, BV, etc.) according to customer needs.


Q2: How long does it take for goods to be delivered to my country?
A2: The delivery time depends on the transport mode and destination country. Generally, sea transport takes 15-30 days, air transport takes 3-7 days, and we will optimize the transport route to shorten the delivery time as much as possible.


Can you provide customs clearance services for dangerous chemicals?
A3: Yes. Our team is proficient in the customs clearance procedures for dangerous chemicals in various countries, and can provide professional compliant declaration and customs clearance services to ensure smooth customs clearance.


Q4: Do you provide customized product and service solutions?
A4: Yes. We can provide personalized product customization and export service solutions according to your specific needs (product specifications, application scenarios, procurement volume, etc.).

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